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The Journal of Vascular and Interventional Radiology and CardioVascular and Interventional Radiology have jointly released the iCARE (Interventional Radiology Checklist for Artificial Intelligence Research Evaluation) guidelines—a comprehensive new framework to improve the transparency, consistency and quality of AI research in interventional radiology. This joint effort outlines best practices and includes a detailed checklist to support the development of safe, generalizable AI tools that enhance IR workflows, improve care delivery and support better patient outcomes. A must-read for researchers, reviewers and anyone working at the intersection of AI and IR.